منابع مشابه
The pharmaco-economics of peri-operative statin therapy.
We analysed the pharmaco-economics of the prospective peri-operative studies of statin administration for major elective vascular surgery, using the NHS reference costs for 2004. This analysis suggests that peri-operative statin therapy for patients undergoing vascular surgery may present the most cost-effective use of statin therapy yet described, with a number-needed-to-treat of 15 and almost...
متن کاملHemodynamic effects of peri-operative statin therapy in on-pump cardiac surgery patients
BACKGROUND Peri-operative statin therapy in cardiac surgery cases is reported to reduce the rate of mortality, stroke, postoperative atrial fibrillation, and systemic inflammation. Systemic inflammation could affect the hemodynamic parameters and stability. We set out to study the effect of statin therapy on perioperative hemodynamic parameters and its clinical outcome. METHODS In a single ce...
متن کاملPeri-Operative High-Dose v Post-Operative Low Dose Steroid Therapy in the Management of Biliary Atresia: a Preliminary Report
Background: The use of high-dose steroid therapy peri portoenterostomy may have a positive impact on the frequency of cholangitis and survival rate. Methods: A prospective study was conducted on two groups of patients (less than three months of age) suffering from biliary atresia from 1999 to 2005. The patients in group I (G I) were managed peri-operatively by high-dose methylprednisolone while...
متن کاملPeri-operative fluid strategy and post-operative acute kidney injury in cardiac surgery patients: any role for pre-operative statin therapy?
Acute kidney injury (AKI) is a common complication associated with increased morbidity and mortality in cardiac surgery patients. In this context, the recent paper by Kim et al., showing that a peri-operative liberal ‘salineand starch-based’ fluid management significantly enhanced the incidence of severe post-operative AKI in off-pump cardiac surgery patients, is to be acclaimed [1]. With regar...
متن کاملInvestigation of predictors of increased creatine kinase levels following vascular surgery and the association with peri-operative statin therapy
UNLABELLED Although peri-operative statin administration is likely to be cardioprotective, there remains a concern about the risk of rhabdomyolysis and associated renal failure following statin administration in the peri-operative period. The aim of this study was to determine independent predictors of creatine kinase (CK) elevation following vascular surgery. DESIGN A retrospective cohort st...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2009
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.2008.05801.x